Shrewdness that maybe came unstuck at first (6)
I believe the answer is:
acumen
'shrewdness' is the definition.
(acumen is a kind of shrewdness)
I can't explain the remainder of the clue.
Can you help me to learn more?
(Other definitions for acumen that I've seen before include "perspicacity" , "Insightfulness" , "Sharpness, penetration, quickness of perception" , "Shrewdness, intelligence in business" , "Shrewdness, sharpness of mind" .)