Shrill South American native starts to call help, yelling (8)
I believe the answer is:
screechy
'shrill' is the definition.
(thesaurus)
'south american native starts to call help yelling' is the wordplay.
'south american native' becomes 'scree' (I am not sure about this - if you are sure you should give a lot more credence to this answer).
'starts to' says to take the initial letters.
The first letters of 'call help yelling' is 'chy'.
'scree'+'chy'='SCREECHY'
Can you help me to learn more?
(Other definitions for screechy that I've seen before include "Shrieky" , "Loud and shrill" , "Harsh and shrill" , "Loud, harsh, piercing" , "calling loudly" .)