Shut up and run! (4)
I believe the answer is:
bolt
I believe this clue is a double definition.
'shut up' is the first definition.
(thesaurus)
'run' is the second definition.
(I've seen this in another clue)
'and' is the link.
(Other definitions for bolt that I've seen before include "playwright" , "From the blue, it's a great surprise" , "Sprint? Yes he does!" , "Lightning flash, fasten" , "wolf" .)