Shyster, I assume, conceals agitation (8)
I believe the answer is:
hysteria
'agitation' is the definition.
(both can mean a state of distress)
'shyster i assume conceals' is the wordplay.
'conceals' indicates a hidden word.
'HYSTERIA' can be found hidden inside 'shyster i assume'.
(Other definitions for hysteria that I've seen before include "Frenzied emotional state" , "display of wild emotion" , "Delirium - nervous disorder" , "frenzied excitement" , "Psychoneurotic condition" .)