Crossword Genius

Sibling has run out? Damn! (6)

Ross

I believe the answer is:

bother

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'damn' is the definition.
(both are expressions of annoyance)

I don't understand how the rest of the clue works.

Can you help me to learn more?

(Other definitions for bother that I've seen before include "Discommode, annoy" , "Irritate - concern oneself" , "Fuss and irritant" , "Badger" , "Annoy or pester" .)

I've seen this clue in The Times.
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