Sick queen saved by extraordinary messiah (9)
I believe the answer is:
squeamish
'sick' is the definition.
(thesaurus)
'queen saved by extraordinary messiah' is the wordplay.
'queen' becomes 'qu' (abbreviation for queen).
'saved by' indicates putting letters inside (I've seen this in other clues).
'extraordinary' is an anagram indicator.
'messiah' is an anagram of 'seamish'.
'qu' put into 'seamish' is 'SQUEAMISH'.
(Other definitions for squeamish that I've seen before include "Easily sickened or disgusted" , "faint-hearted" , "Easily shocked, sickened" , "Easily shocked by blood and gore" , "Queasy" .)