Sign from mortgage minister (6)
I believe the answer is:
gemini
'sign' is the definition.
(Gemini is a star sign)
'from mortgage minister' is the wordplay.
'from' indicates the answer is hidden within the clue.
'GEMINI' can be found hidden inside 'mortgage minister'.
(Other definitions for gemini that I've seen before include "May person" , "set of twinklers" , "House" , "space programme" , "star group" .)