Crossword Genius

Sign of illness? (6)

Ross

I think it could be either:

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6

7

cancer

This clue is a double definition.

'sign' is the first definition.
(sign of the zodiac)

'illness?' is the second definition.
(cancer is a kind of health problem)

'of' acts as a link.

(Other definitions for cancer that I've seen before include "Crab star sign" , "Malignant growth and sign of the zodiac" , "Sign of the Crab, or a Tropic" , "Fourth sign of the zodiac" , "A Tropic or a malignant disease" .)

I've seen this clue in The Telegraph.
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