Simplify, with "down" (4)
I believe the answer is:
boil
(Other definitions for boil that I've seen before include "7 in water" , "Sore with a hard core filled with pus" , "Abscess" , "Bubble up - inflamed swelling" , "Eruption of the skin" .)
I believe the answer is:
boil
(Other definitions for boil that I've seen before include "7 in water" , "Sore with a hard core filled with pus" , "Abscess" , "Bubble up - inflamed swelling" , "Eruption of the skin" .)