Singles out a nose (4)
I believe the answer is:
ones
'singles' is the definition.
('one' can be a synonym of 'single')
'out a nose' is the wordplay.
'out' indicates anagramming the letters.
'nose' with letters rearranged gives 'ONES'.
(Other definitions for ones that I've seen before include "Units" , "(Of ship) returning to port of origin" , "1 & 1 & 1" , "Aces" , "Singles" .)