Sister translating runes (5)
I believe the answer is:
nurse
'sister' is the definition.
(I've seen this before)
'translating runes' is the wordplay.
'translating' indicates an anagram.
'runes' anagrammed gives 'NURSE'.
(Other definitions for nurse that I've seen before include "Medical carer" , "Minister to" , "Look after: entertain" , "One ministering to the sick" , "Hospital employee" .)