Sisters -- one in France in the outskirts of Nimes (4)
I believe the answer is:
nuns
'sisters' is the definition.
(I've seen this before)
'one in france in the outskirts of nimes' is the wordplay.
'one in france' becomes 'un' (**).
'in the' indicates putting letters inside.
'outskirts of' suggests removing the centre.
'nimes' with its centre taken out is 'ns'.
'un' placed within 'ns' is 'NUNS'.
(Other definitions for nuns that I've seen before include "women in order" , "Sisters in order" , "Religious community members" , "Religious sisters" , "Convent residents" .)