Site of the most famous oracle of Apollo (6)
I believe the answer is:
delphi
(Other definitions for delphi that I've seen before include "Ancient Greek sanctuary dedicated to Apollo" , "Where Apollo's most famous oracle spoke in Greece" , "'Ancient Greek city, site of the oracle (6)'" , "Home of the oracle on the slopes of Mount Parnassus" , "Ancient Greek city, site of famous oracle" .)