Sixth sense possessed by Dorothy finds tyrant (6)
I believe the answer is:
despot
'tyrant' is the definition.
('despot' can be a synonym of 'tyrant')
'sixth sense possessed by dorothy' is the wordplay.
'sixth sense' becomes 'esp' (I've seen this in other clues).
'possessed by' indicates putting letters inside.
'dorothy' becomes 'dot' (nickname for someone called Dorothy).
'esp' inserted into 'dot' is 'DESPOT'.
'finds' is the link.
(Other definitions for despot that I've seen before include "Cruel and oppressive dictator" , "Possibly 4 [CZAR]" , "Person with more than enough power" , "A ruler with unrestricted power" , "Absolute ruler, tyrant" .)