Skilful handling of rampant tulip mania working (12)
I believe the answer is:
manipulation
'skilful handling' is the definition.
'manipulation' can be an answer for 'handling' (synonyms). I'm not sure about the 'skilful' bit.
'rampant tulip mania working' is the wordplay.
'rampant' is an anagram indicator (I've seen this in other clues).
'working' becomes 'on' (on can mean working or activated).
'tulip'+'mania'='tulipmania'
'tulipmania' is an anagram of 'manipulati'.
'manipulati'+'on'='MANIPULATION'
'of' is the link.
Can you help me to learn more?
(Other definitions for manipulation that I've seen before include "Osteopathic technique" , "Osteopath's technique" , "Artful control" , "Osteopath's method" .)