Skilful Italian supports a doctor with nothing (6)
I believe the answer is:
adroit
'skilful' is the definition.
(thesaurus)
'italian supports a doctor with nothing' is the wordplay.
'italian' becomes 'it'.
'supports' says to put letters next to each other (bottom letters provide a support for the top ones).
'doctor' becomes 'dr' ('Dr' can be a synonym of 'doctor').
'with nothing' becomes 'o' (I've seen this in other clues).
'a'+'dr'+'o'='adro'
'it' after 'adro' is 'ADROIT'.
(Other definitions for adroit that I've seen before include "Quick or adept" , "Skilful or ingenious" , "Quick and deft" , "resourceful" , "Clever - crafty" .)