Skilled worker is prejudiced, first to come out (7)
I believe the answer is:
artisan
'skilled worker' is the definition.
(I know that artisan is a type of skilled worker)
'prejudiced first to come out' is the wordplay.
'prejudiced' becomes 'partisan' (partisan can mean prejudiced or party political).
'first to come out' means to remove the first letter.
'partisan' with its initial letter taken off is 'ARTISAN'.
'is' is the link.
(Other definitions for artisan that I've seen before include "Mechanic" , "Journeyman" , "Skilled worker at craft or trade" , "one in command of craft?" , "Handy worker" .)