Skin breakout (4)
I believe the answer is:
acne
'skin breakout' is the definition.
(I've seen this in another clue)
This is the entire clue.
(Other definitions for acne that I've seen before include "Face problems" , "Pimply ailment of adolescnce" , "Skin condition prevalent among teenagers" , "sort of disease" , "Problem to face in" .)