Slander from venomous creature, Irish (7)
I believe the answer is:
asperse
'slander' is the definition.
(synonyms)
'venomous creature irish' is the wordplay.
'venomous creature' becomes 'asp' (venomous snake).
'irish' becomes 'erse' (I've seen this before).
'asp'+'erse'='ASPERSE'
'from' is the link.
(Other definitions for asperse that I've seen before include "Malign" , "Accuse falsely" , "Slander, spread false rumours about - as peers may?" , "Slander like Parsees" , "Disparage" .)