Slaughtered considerable number (4)
I believe the answer is:
slew
I believe this is a double definition.
'slaughtered' is the first definition.
(I've seen this before)
'considerable number' is the second definition.
(slew can mean a large number of things)
(Other definitions for slew that I've seen before include "a great number in Chicago" , "Move obliquely or sideways, often losing control" , "twisted position" , "Butchered" , "Large amount - killed intentionally" .)