Slight offensive to me, rebuff not entirely uplifting (6)
I believe the answer is:
remote
'slight' is the definition.
(as in a slight or remote chance)
'offensive to me rebuff not entirely uplifting' is the wordplay.
'not entirely' indicates a hidden word.
'uplifting' says the letters should be written in reverse.
'etomer' is hidden in the letters of 'offensive to me rebuff'.
'etomer' backwards is 'REMOTE'.
(Other definitions for remote that I've seen before include "Far away as meteor (6)" , "gadget" , "Distant (from civilisation?)" , "Far-flung" , "Device for controlling apparatus from a distance" .)