Sloth, e.g.?
(Other definitions for sin that I've seen before include "Serious transgression" , "Immoral act" , "Misdeed" , "trip" , "Transgression of moral law" .)
I've seen this clue in the L.A. Times Daily, the Wall Street Journal, The Washington Post Sunday, The Washington Post and the New York Times.
I've seen this clue in The New York Times.
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