Crossword Genius

Social worker takes one to be an opponent (4)

Ross

I believe the answer is:

anti

'opponent' is the definition.
(I've seen this before)

'social worker takes one' is the wordplay.
'social worker' becomes 'ant' (I've seen this before**).
'takes' means one lot of letters go next to another.
'one' becomes 'i' (Roman numeral).
'ant'+'i'='ANTI'

'to be an' acts as a link.

(Other definitions for anti that I've seen before include "not favoured" , "An opponent - opposed to party policy, etc" , "[NO MAN]" , "Policy's opponent" , "Adversary" .)

I've seen this clue in The Guardian and The Telegraph.
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