Solvent, having lost weight (7)
I believe the answer is:
thinner
'solvent' is the definition.
(synonyms)
I cannot understand how the rest of the clue works.
Can you help me to learn more?
(Other definitions for thinner that I've seen before include "Slenderer" , "Volatile liquid" , "Skinnier" , "what one adds to paint" , "More flimsy" .)