Some of the regular guests have a different opinion (5)
I believe the answer is:
argue
'have a different opinion' is the definition.
'argue' can be an answer for 'have' (thesaurus). I'm not sure about the 'a different opinion' bit.
'some of the regular guests' is the wordplay.
'some of' indicates a hidden word.
'ARGUE' is hidden within 'regular guests'.
Can you help me to learn more?
(Other definitions for argue that I've seen before include "Contend with reasoning" , "Altercate" , "Squabble" , "Debate, contend" , "Fall out" .)