Some rockets send astronauts the wrong way, creating misery (7)
I believe the answer is:
sadness
'misery' is the definition.
(thesaurus)
'some rockets send astronauts the wrong way' is the wordplay.
'some' says the answer is hidden in the clue (some of the parts of the word are used).
'the wrong way' is a reversal indicator.
'ssendas' can be found hidden inside 'rockets send astronauts'.
'ssendas' in reverse letter order is 'SADNESS'.
'creating' acts as a link.
(Other definitions for sadness that I've seen before include "Dolour" , "Despondency" , "Emotion experienced when unhappy" , "Depression" , "distress" .)