Somehow resign as a musician (6)
I believe the answer is:
singer
'a musician' is the definition.
(I know that singer is a type of musician)
'somehow resign' is the wordplay.
'somehow' is an anagram indicator.
'resign' anagrammed gives 'SINGER'.
'as' is the link.
(Other definitions for singer that I've seen before include "Musical sounds" , "Coventry car firm" , "inventor who got everything sewn up?" , "Vocal performer" , "Eg, tenor" .)