Son of Isaac and Rebecca (4)
I believe the answer is:
esau
<span class="explanation-format__ClueExplanation">'<span class="explanation-format__original">son of isaac and rebecca</span>' is the definition.<br/ ><span class="explanation-format__explanation">(I've seen this before)</span><br/ ><br/ >This is all the clue.<br/ ></span>
(Other definitions for esau that I've seen before include "Jacob's twin (Bible)" , "Biblical man who sold his birthright for a mess of pottage" , "First son of Isaac (Bible)" , "Jacob's twin brother" , "Rebecca's son" .)