Soother (4)
I believe the answer is:
balm
'soother' is the definition.
(cream that soothes skin)
This is the entire clue.
(Other definitions for balm that I've seen before include "that will soothe the skin" , "It comforts, soothes" , "Unguent" , "Soothing herb" , "It's comforting" .)