Soothing salve (4)
I believe the answer is:
balm
'soothing salve' is the definition.
(I've seen this in another clue)
This is all the clue.
(Other definitions for balm that I've seen before include "Something soothing" , "Soothing ointment for lamb (4)" , "Royal holiday residence on the River Dee" , "A soothing influence on lamb" , "'Ointment, salve (4)'" .)