Sound from hooter around middle of shift (5)
I believe the answer is:
noise
'sound' is the definition.
(noise is a kind of sound)
'hooter around middle of shift' is the wordplay.
'hooter' becomes 'nose' (I've seen this before).
'around' means one lot of letters goes inside another.
'middle of' indicates the central letters.
The middle of 'shift' is 'i'.
'nose' enclosing 'i' is 'NOISE'.
'from' acts as a link.
(Other definitions for noise that I've seen before include "Unpleasant sounds" , "Virgil's birthplace" , "Clamour" , "Unstructured sound" , "Racket, din" .)