Sound from organ -- one's enthralled (5)
I believe the answer is:
noise
'sound' is the definition.
(a noise is a sound)
'organ one's enthralled' is the wordplay.
'organ' becomes 'nose' (nose is a kind of organ).
'one' becomes 'i' (Roman numeral).
'enthralled' means one lot of letters goes inside another.
'nose' going around 'i' is 'NOISE'.
'from' is the link.
(Other definitions for noise that I've seen before include "Public talk" , "Fuss" , "Unwelcome sound" , "interference" , "Sound - gossip" .)