Sound of dogs in East London location (7)
I believe the answer is:
barking
I believe this clue is a double definition.
'sound of dogs' is the first definition.
'east london location' is the second definition.
'in' is the link.
(Other definitions for barking that I've seen before include "London suburb ..." , "Mad - town forming a London borough with Dagenham" , "Completely mad" , "Area of London - mad?" , "up the pole" .)