Source of misery is wailing female (she is wasted) (4)

I believe the answer is:

bane

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'source of misery' is the definition.
(I've seen this before)

I don't understand the remainder of the clue.

(Other definitions for bane that I've seen before include "Cause of great distress, rhymes with rule" , "scourge" , "Source of misery" , "Something causing misery or distress" , "A fatal poison" .)

I've seen this clue in The Independent.

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