Souvenir from some uplifting city -- Rome, maybe (6)
I believe the answer is:
memory
'souvenir' is the definition.
(thesaurus)
'some uplifting city rome maybe' is the wordplay.
'uplifting' is a reversal indicator.
'some' says the answer is hidden in the clue (some of the parts of the word are used).
'yromem' is hidden in the letters of 'city rome maybe'.
'yromem' reversed gives 'MEMORY'.
'from' acts as a link.
(Other definitions for memory that I've seen before include "commemoration" , "Recollection" , "Power of recall" , "(Computer) data store" , "The ability to store things in mind, and to recall (6)" .)