Space found in A&E: surprised? (5)
I believe the answer is:
agape
'surprised?' is the definition.
(thesaurus)
'space found in ae' is the wordplay.
'space' becomes 'gap' (gap is a kind of space).
'found in' is an insertion indicator.
'gap' placed into 'ae' is 'AGAPE'.
(Other definitions for agape that I've seen before include "love a Christian shows" , "Astonished" , "Christian feast" , "religious feast" , "Christian's love" .)