Space programme's latest? Look amazed (4)
I believe the answer is:
gape
'look amazed' is the definition.
(to gape is to stare open-mouthed in amazement)
'space programme's latest?' is the wordplay.
'space' becomes 'gap' (gap is a kind of space).
'latest?' indicates one should take the final letters (I've seen 'latest' mean this).
The last letter of 'programme' is 'e'.
'gap'+'e'='GAPE'
(Other definitions for gape that I've seen before include "Yawn" , "Appear amazed" , "Failure to meet" , "Stare at page" , "Stare with open mouth in wonder" .)