Special bed made low (10)
I believe the answer is:
despicable
'low' is the definition.
(synonyms)
'special bed made' is the wordplay.
'made' indicates anagramming the letters.
'special'+'bed'='specialbed'
'specialbed' with letters rearranged gives 'DESPICABLE'.
(Other definitions for despicable that I've seen before include "bum" , "Mean" , "Vile" , "rotten" .)