Spice seen in stone cask from the East (6)
I believe the answer is:
'spice' is the definition.
(I know that Nutmeg is a spice)
'stone cask from the east' is the wordplay.
'stone' becomes 'gem' (a gemstone).
'cask' becomes 'tun' (tun is a kind of cask).
'from the east' is a reversal indicator (on a map from right to left).
'gemtun' in reverse letter order is 'NUTMEG'.
'seen in' is the link.
(Other definitions for nutmeg that I've seen before include "Kernel and girl for a spice" , "(In soccer) kick the ball between an opponent's legs" , "Aromatic seed - met gnu (anag)" , "Hard seed of tropical tree grated for spice" , "Hard seed used as seasoning" .)