Spice starts to change unappetising milkshake into nectar (5)
I believe the answer is:
cumin
'spice' is the definition.
(cumin is a spice)
'starts to change unappetising milkshake into nectar' is the wordplay.
'starts to' suggests taking the first letters.
The initial letters of 'change unappetising milkshake into nectar' is 'CUMIN'.
(Other definitions for cumin that I've seen before include "Curry powder ingredient" , "seasoning" , "Spice used in chilli and curry powder" , "Curry-seasoning herb" , "Mediterranean plant with aromatic seeds" .)