Spider natural at spinning (9)
I believe the answer is:
tarantula
'spider' is the definition.
(I know that tarantula is a type of spider)
'natural at spinning' is the wordplay.
'spinning' is an anagram indicator.
'natural'+'at'='naturalat'
'naturalat' with letters rearranged gives 'TARANTULA'.
(Other definitions for tarantula that I've seen before include "Leggy creature" , "hairy creature" , "small, venomous creature" , "Creepy-crawly" , "Hairy arachnid" .)