Spike, large one (4)
I believe the answer is:
lace
'spike' is the definition.
(synonyms)
'large one' is the wordplay.
'large' becomes 'L' (eg in clothes sizes).
'one' becomes 'ace' (ace has a value of one in some card games).
'l'+'ace'='LACE'
(Other definitions for lace that I've seen before include "Do up (shoe, etc)" , "Fine open fabric" , "Delicate material" , "Shoe tie" , "Shoe string" .)