Spike troublemaker's drink (6)
I believe the answer is:
impale
'spike' is the definition.
('impale' can be a synonym of 'spike')
'troublemaker's drink' is the wordplay.
'troublemaker' becomes 'imp' (I've seen this before).
'drink' becomes 'ale' (ale is a kind of drink).
'imp'+'ale'='IMPALE'
(Other definitions for impale that I've seen before include "Run through with stake" , "Spike" , "Kill by piercing with a sharp stake" , "Pierce, run through" , "Pierce, me pail (anag.)" .)