Spine-tingling sign of things to come (4)
![Ross](/clue/static/ross-mug.min.png)
I believe the answer is:
omen
(Other definitions for omen that I've seen before include "Augur" , "Straw in the wind" , "Event regarded as a prophetic sign of good or evil" , "Portent of evil" , "Harbinger, prophetic sign" .)