Spouse carelessly works (6)
I believe the answer is:
opuses
'works' is the definition.
(an opus is a creative work)
'spouse carelessly' is the wordplay.
'carelessly' indicates an anagram.
'spouse' with letters rearranged gives 'OPUSES'.
(Other definitions for opuses that I've seen before include "pieces of music" , "Musical works" .)
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