Spreading widely, pain vexes drunk (9)
I believe the answer is:
expansive
'spreading widely' is the definition.
'expansive' can be an answer for 'spreading' (thesaurus). I'm unsure of the 'widely' bit.
'pain vexes drunk' is the wordplay.
'drunk' indicates an anagram.
'pain'+'vexes'='painvexes'
'painvexes' anagrammed gives 'EXPANSIVE'.
Can you help me to learn more?
(Other definitions for expansive that I've seen before include "Tending to get bigger" , "Wide-ranging" , "Talkative" , "Covering a wide area" , "Genial" .)