Stand last of booze in pub (4)
I believe the answer is:
bear
'stand' is the definition.
('bear' can be a synonym of 'stand')
'last of booze in pub' is the wordplay.
'last of' suggests the final letters.
'in' means one lot of letters goes inside another.
'pub' becomes 'bar' (I've seen this before).
The final letter of 'booze' is 'e'.
'e' inserted inside 'bar' is 'BEAR'.
(Other definitions for bear that I've seen before include "See 13 across" , "Support; produce (fruit)" , "Shoulder - stomach" , "Put up with - speculator" , "Support; brutish person" .)