Standard in London or Manchester (4)
I believe the answer is:
norm
'standard' is the definition.
(I know that norm is a type of standard)
'in london or manchester' is the wordplay.
'in' indicates the answer is hidden within the clue.
'NORM' is hidden in the letters of 'london or manchester'.
(Other definitions for norm that I've seen before include "Rule; average" , "Standard, average" , "Average result" , "Standard amount or customary behaviour" , "Average level of performance" .)