Start again - October is crazy with Charlie missing (6)
I believe the answer is:
reboot
'start again' is the definition.
(I've seen this before)
I can't explain the remainder of the clue.
Can you help me to learn more?
(Other definitions for reboot that I've seen before include "Start (computer) again" , "Start up a computer's initial program again" , "Start notebook again" , "Re-start up a computer's initial program" , "Recover from crash" .)