Starters for our first part of meal, naturally (2,6)
I believe the answer is:
of course
'naturally' is the definition.
(synonyms)
'starters for our first part of meal' is the wordplay.
'starters for' suggests taking the first letters.
'part of meal' becomes 'course' ('course' is part of 'meal').
The first letters of 'our first' is 'of'.
'of'+'course'='OF COURSE'
(Other definitions for of course that I've seen before include "Definitely" , "Certainly, without a doubt" , "Naturally, as one would expect" , "Naturally, goes without saying" , "need I say" .)